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HYPER: In Vivo Localized Magnetic Theranostic Platform
說明
HYPER: in vivo 磁性Theranostic平臺。

HYPER 是第一個用於小型動物的商用化影像磁力導引加溫 (magnetic fluid hyperthermia, MFH) 系統。HYPER 技術利用磁梯度進行定位,如磁粒子成像 (MPI),在稱為無場區域 (FFR) 的敏感區域內產生奈米粒子的局部加熱。
FFR 可同時調整尺寸和位置,結合射頻振幅調整,允許使用者控制加熱到毫米尺度以及即時光纖溫度監測。HYPER 是磁性溫熱治療、藥物釋放和細胞活化研究方法的突破性研究工具。
HYPER 可作為獨立系統提供,可與 MOMENTUMTM 磁粒子成像 (MPI) 工作流程或其他斷層成像模式(如光學、PET、MRI 和 X 射線/CT)集成。

特點:
1. 帶基準的滑鼠運輸床。
2. 雙平面光學攝像機。
3. 智能化MPI MOMENTUM圖像結合。
4. 支援大多數3D呈像方法,可用ICOM 格式導入。
5. 監控即時光纖溫度感測器(兩個通道)
6. 脈衝治療序列的軟體控制。

Link to Magnetic Insight
Description
HYPER: In Vivo Localized Magnetic Theranostic Platform

HYPER is the first commercially available localized, image-guided magnetic fluid hyperthermia (MFH) system for small animals. Using magnetic gradients for localization like magnetic particle imaging (MPI), the HYPER technology produces localized heating of nanoparticles within a sensitive region known as the Field-Free Region (FFR).
The FFR can be adjusted in both size and position, which, in conjunction with RF amplitude adjustment, allows the user control of heating to millimeter-scales along with real-time fiber optic temperature monitoring. HYPER is a ground-breaking research tool for magnetic thermal ablation, drug release, and cell activation models.

HYPER is available as a stand-alone system that can be integrated with the MOMENTUMTM Magnetic Particle Imaging (MPI) workflow or other tomographic imaging modalities such as optical, PET, MRI and X-ray/CT.
Features
• Mouse transport bed with fiducials
• Biplanar optical cameras registration
• Simple co-registration to MPI MOMENTUM images
• Supports co-registration of imported DICOM formats of most imaging modalities.
• Real time fiber optic temperature sensors for monitoring (two channels)
• Software controls for pulsed treatment sequences

Specifications
• Bore size: 4 cm (maximum diameter of animal and carriage)
• Available heating area: 4 x 4 x 10 cm
• Field gradient: Variable selection from 0.5 T/m to 2.0 T/m
• Radio Frequency: Field selection from 340 kHz to 20 mT continuous
• Weight: 400 kg (882 lbs)
• Width of 1.5 m (60 inches)
• Depth of 1.5 m (60 inches)
• Height of 2.0 m (79 inches)

Link to Magnetic Insight
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