HYPER: In Vivo Localized Magnetic Theranostic Platform
HYPER is the first commercially available localized, image-guided magnetic fluid hyperthermia (MFH) system for small animals. Using magnetic gradients for localization like magnetic particle imaging (MPI), the HYPER technology produces localized heating of nanoparticles within a sensitive region known as the Field-Free Region (FFR).
The FFR can be adjusted in both size and position, which, in conjunction with RF amplitude adjustment, allows the user control of heating to millimeter-scales along with real-time fiber optic temperature monitoring. HYPER is a ground-breaking research tool for magnetic thermal ablation, drug release, and cell activation models.
HYPER is available as a stand-alone system that can be integrated with the MOMENTUMTM Magnetic Particle Imaging (MPI) workflow or other tomographic imaging modalities such as optical, PET, MRI and X-ray/CT.
Features
• Mouse transport bed with fiducials
• Biplanar optical cameras registration
• Simple co-registration to MPI MOMENTUM images
• Supports co-registration of imported DICOM formats of most imaging modalities.
• Real time fiber optic temperature sensors for monitoring (two channels)
• Software controls for pulsed treatment sequences
Specifications
• Bore size: 4 cm (maximum diameter of animal and carriage)
• Available heating area: 4 x 4 x 10 cm
• Field gradient: Variable selection from 0.5 T/m to 2.0 T/m
• Radio Frequency: Field selection from 340 kHz to 20 mT continuous
• Weight: 400 kg (882 lbs)
• Width of 1.5 m (60 inches)
• Depth of 1.5 m (60 inches)
• Height of 2.0 m (79 inches)
Link to Magnetic Insight