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Microfludic chip
說明
Lunatic – 次世代 微量分光光度計

2μL ,Accuracy < 2%, Precision < 1%, spectral unmixing


 RNA DNA 傻傻分不清楚?

有想過你的DNA樣品中又多少的濃度是RNA貢獻的嗎?或是反過來?Lunatic 搭配先進的光譜拆解功能 不只可以拆分污染物,也可區分RNA與DNA,並計算算出個別的濃度. 使用unmix功能量測的DNA濃度與picogreen的濃度成高度正相關,文獻中比較48萬筆測量結果中,其相關性 r = 0.86,成高度正相關.

重新定義超微量分光光譜儀

超微量分光光度計不只是拿來做為樣品的評估而已!使用兩個固定光徑的Lunatic,擁有 Accuracy within 1% 與 Precision within 1% 的準確度、實測抗體濃度 2.35 - 201.4 mg/ mL 範圍內,R2高達0.9999!而一切只需要2μL的樣品!

Unmix - 拆分藏在樣品內的不單純

常常覺得核酸與蛋白質濃度怪怪的嗎?搞不清楚是 樣品的問題還是有殘留?Lunatic具備光譜拆解的功能,可辨識並區分常見污染物並移除其干擾.不只 可以計算出真實濃度,也作為純化品管的參考

符合USPPh.Eur.UV/Vis量測之規範

Luantic 提供符合USP <857>與Ph.Eur. 2.2.2.25對 於UV/Vis光度計規範的測試程序與標準品,也具有 完善的文件與儀器性能測試程序、文件與標準品. Lunatic已在各大藥廠服役,儀器的適用性已被廣泛接受.

High Lunatic Plate

Lunatic Plate/Strip 是高精度微流道系統,具有兩個固定光徑.可使用8爪上樣,亦適用於自動化分注系統.特殊的Reservoir設計,不用擔心上樣前樣品的蒸散.原廠測試,分注後兩小時內樣品的吸收值部會有觀察得到的改變.

法規? 確校? 沒問題

Lunatic符合USP & Ph. Eur對於吸收光譜方法學的規範,並提供 NIST 標準品、IOQ文件與支援21 CFR Part11規範的軟體。Unchained labs的產品已被廣大生物製劑廠採用。





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Description
Lunatic - The next-gen protein and nucleic acid quantification system.


Get your quant on


Lunatic makes batch quantification of protein, DNA and RNA a no-brainer. All you need is 2 μL and 10 minutes to measure up to 96 samples. Run them straight-up, even at high concentrations, without ever diluting. Lunatic gets biologics and genomics UV/Vis quantification on the money every time. Just drop, load and read.


2 µL volume

96 samples

10 minutes

SBS plate format


No B.S. workflow

Skip the sample prep, cleaning and worrying about cross-contamination or evaporation – your samples will sit tight for up to 2 hours. Our Lunatic plate runs 96 samples in 10 minutes. Each microfluidic circuit has two fixed pathlengths built-in to cover a wide dynamic range of 0.03-275 OD. All you do is load up your samples and get kick-ass results. 


Max out your biologic

Lunatic is the only system out there that can measure biologics at high-throughput and high concentration. It’s got dynamic range that covers from 0.02 mg/mL to 200 mg/mL (mAb), so run any protein without ever having to dilute again. Stop the madness of running just one protein at a time — and cleaning up afterwards. 


Ridiculously good data 


Get spot-on precision within 1% and accuracy within 2%. Using two fixed pathlengths, Lunatic gets you jaw-dropping data at both low and high protein concentrations and nails the expected concentrations every time. With the smallest sample size, the highest throughput and crazy accurate results, Lunatic is hands down the best tool out there for protein quantification


Accuracy you can show off 

Lunatic has shocking accuracy and wants to prove it. Using the Fundamentals tryptophan standards, the accuracy, precision and linearity of the instrument can be proven at any time — at the protein-relevant 280 nm wavelength and OD range of 20-225. Be confident about every sample with data that leaves no room for doubt. 


Downstream ready 


Smash through the USP & Ph. Eur. UV/Vis requirements for absorbance accuracy, precision, linearity, wavelength accuracy, stray light and resolution with performance verification measurements of independently certified NIST standards. Lunatic is ready when you are to get validated and make the move into QC. 


Put it on lockdown 


GLP labs don’t sweat it. Lunatic’s software hooks labs up with 21 CFR Part 11 compliant features. We’re talking password protection, electronic signatures, full audit trail — the whole package. 


Dig up your genomic’s dirt 


DNA and RNA samples can be freaking messy. Lunatic analysis software lets you see annoying impurities that classic A260 measurements alone mistake as your DNA or RNA. Find out exactly how much RNA, turbidity, beads and other influencers are screwing up your nucleic acid quantification. Ditch the time-sucking, dye-based prep and know right away if your samples are good to go. 


Set it and forget it 


Lunatic talks to robots. Hook it up with any liquid handler system and run your measurements completely hands-off with our API setup and keep more of your precious sample for the rest of your workflow. 

 



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