UltraMicroscope Choros™｜大樣本 3D 層光顯微平台

English Product Overview

UltraMicroscope Choros™ - Advanced Large-Sample 3D Light Sheet Microscopy Platform

The UltraMicroscope Choros™ represents a breakthrough in light sheet microscopy technology, specifically designed for high-resolution 3D imaging of large cleared specimens. Building upon the trusted foundation of the UltraMicroscope Blaze™ platform, the Choros significantly expands research capabilities by offering an enlarged sample cuvette and extended stage travel range, resulting in twice the imaging volume compared to the standard Blaze configuration.

This revolutionary system enables researchers to image specimens as large as whole mice at high resolution (30x magnification achieved through 12x objective lens with 2.5x built-in post-magnifier) without the need for sectioning or tedious image stitching. The proprietary MI-Plan multi-immersion objective lenses are specifically engineered for light sheet imaging of large samples, providing exceptional optical performance with long working distances, high numerical apertures, and flat-field correction.

Key technical specifications include a 4.2 megapixel CMOS camera with 2048 x 2048 pixel resolution and 6.5 µm pixel size, triple bidirectional static light sheet optics, and compatibility with water, aqueous, and organic imaging media through multiple dipping cap configurations. The system features white light laser excitation with filter wheels, enabling broad fluorophore compatibility for multiplex imaging applications.

The UltraMicroscope Choros™ is fully compatible with Miltenyi Biotec's pioneering LightSpeed Mode, dramatically accelerating imaging processes while maintaining image quality. This makes it ideal for time-sensitive applications and reduces photobleaching effects. The system integrates seamlessly with MACS® iQ View 3D Large Volume software, providing comprehensive image processing, analysis, and visualization capabilities specifically designed for large-volume datasets.

Research applications span developmental biology with whole embryo developmental tracking, neuroscience including whole-brain neural network mapping, cancer research for tumor microenvironment analysis, drug development for preclinical efficacy assessment, large cohort studies requiring high-throughput sample analysis, and spatial biology applications with multiplex labeling analysis.

The automated imaging options, combined with the large cuvette and high-throughput MACS® UltraMount workflows, enable multiple sample imaging for extremely efficient workflow optimization in large cohort studies such as preclinical research, developmental biology investigations, and drug testing protocols. This represents a significant advancement for research institutions requiring comprehensive tissue analysis capabilities.

The system maintains the core excellence of the Blaze platform while extending capabilities for larger specimen analysis, ensuring researchers do not need to compromise on hardware quality or image resolution when studying large specimens. With its professional-grade construction, advanced optical design, and comprehensive software integration, the UltraMicroscope Choros™ sets new standards for large-sample light sheet microscopy applications in academic and industrial research environments.