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Luxonus PAI system
Luxonus PAI system Photoacoustic Photoacoustic Photoacoustic
Luxonus PAI system
Photoacoustic
Photoacoustic
Photoacoustic

LUXONUS - Photoacoustic 3D Imaging（PAI）

Luxonus 3D小鼠光聲成像系統 – 不用染色，提供血管位置與血液含氧量資訊！

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說明

 Photoacoustic Imaging (PAI)

Photoacoustic imaging 結合兩種科技：紅外脈衝雷射與超音波，利用紅外雷射的高精準度與穿透率，產生光聲效應，發出聲波，再利用矩陣聲學接收器接收定位訊號．如此設計，可達到高穿透厚度，以及避免自體螢光的干擾．

什麼是光聲訊號？

光聲現象是指物體在周期性變化的光照下產生聲信號的現象。光聲效應的產生是由於在光的照射下物體能量增加，局部聚集的能量以熱的形式釋放出來從而引起周圍物質的震動。震動的頻率取決於光信號的頻率，而強度則與材料、幾何形狀等物體自生性質有關*．

光聲原理簡介說明

因為是利用光學吸收的特性發出聲學訊號，因此可以利用物體光學吸收的特性，利用不同波長的雷射區分物質，在生物體中，最直覺地利用就是區分含氧量血與缺氧血的差異．在光聲影像系統中，在做label free血管造影時，可以很輕易的區分血管含氧量．

光聲系統在血管造影上的優勢

很多技術都可以進行血管造影，但僅止於較大型的血管．光聲技術把血管造影提升至另一個層次．空間解析度可達100µm，可以看到小型的動脈與靜脈，輔以氧氣飽和度，讓in vivo實驗中對血管了解更近一步．

Luxonus 小動物光聲影像系統

Luxonus光聲影像系統，起源於2014年日本ImPACT革新研究開發計畫，於2018年從京都大學與慶應義塾大學的研究人員創立公司，參與了日本J-Startup計畫，發展創新的光聲影像系統．小動物研究用影像系統於2021年10月發表，並全力發展臨床用影像裝置．
Luxonus光聲影像系統採用平台式設計，除了不需要手持探頭降低操作門檻，也加大了超音波探頭陣列的尺寸，採用直徑22mm半球形探頭陣列，與180mm×290mm 的掃描範圍，從小鼠到巨型Rat都可以拍攝．

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* (Wikipedia)
Description

We are willing to provide innovative technology to the medical

 

Luxonus Inc. is developing a diagnostic imaging system that uses photoacoustic 3D imaging (PAI) technology, which combines light and ultrasound, to safely and easily capture ultra-high-resolution 3D images without exposure.

This new technology enables us to obtain morphological and functional information on blood vessels and lymphatic vessels, which will provide a comprehensive picture of the disease onset, the healing process, and pre- and post-illness health conditions.

For example, it is expected to bring about innovations in future medical care, such as utilizing the information for preoperative diagnosis and early determination of treatment effects, and enabling the selection of the most appropriate treatment for individuals who have been difficult to treat.

 

Photoacoustic 3D Imaging（PAI）

 

PAI is a technology that uses a special sensor to receive ultrasound waves generated when pulsed light is irradiated to a living body, and computer analysis is used to create images from the received data.

Compared to existing imaging technologies such as ultrasound, X-ray computed tomography (CT), and magnetic resonance imaging (MRI), new diagnostic imaging equipment using PAI enables ultra-high resolution 3D imaging of blood vessels with no exposure and no invasiveness (no contrast agent used).

In addition, hemoglobin oxygen saturation and lymphatic vessels can be visualized, which is expected to be utilized for preoperative planning and verification of medication effects.

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