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Viscover™ 高品質造影劑專家
小動物影像研究的卓越選擇
Viscover™ 嚴格把關品質，提供 MRI、CT、超音波與光學影像等多種造影劑。從小分子到奈米粒子的多元結構設計，操作簡便、效率出色，滿足各種影像需求。
Viscover™ Imaging Agents Portfolio
隨著動物影像技術在藥物研發領域的重要性日益提升，Viscover™ 很榮幸能為您提供一套完整且專業的臨床前影像造影劑產品組合，涵蓋主要影像模態——這是業界首創的完整解決方案。運用創新的奈米技術（nano-technologies），我們的多數造影劑遠超越人類臨床常規標準，同時我們也提供符合臨床標準的造影劑選項。
MRI Portfolio
Contrast agents that will transform your pre-clinical MRI facility
GadoSpin™ 與 FeraSpin™ 系列造影劑，專為磁振造影（MRI）設計，提供卓越的影像對比度和穩定性，讓您的臨床前 MRI 設施發揮最大效能。
CT Portfolio
Superior contrast for exceptional CT imaging results
ExiTron™ 系列造影劑，專為電腦斷層掃描（CT）影像優化，提供優異的對比效果和長時間影像窗口，實現卓越的 CT 影像成果。
Ultrasound Portfolio
Enhanced ultrasound contrast for precise diagnostics
PolySon™ 系列造影劑，專為超音波影像設計，提供增強的對比度和清晰度，實現精準的診斷影像效果。
Optical Portfolio
Advanced optical imaging for cutting-edge research
NiraWave™ 與 FluoroWave 系列，提供螢光影像和光學影像解決方案，適用於特定應用的螢光造影，支援尖端研究需求。
Chemistry Portfolio
Customized chemical solutions for your specific needs
客製化化學解決方案，根據您的特定研究需求量身打造，從造影劑開發到藥物製造，提供全方位的化學技術支援。
Viscover™ 核心優勢
Quality | 品質卓越
Viscover™ 是小動物體內影像（Small Animal In Vivo Imaging）領域的里程碑。這個創新的產品組合專注於提供高品質的臨床前研究造影劑（Pre-clinical Imaging Agents）。
Viscover™ 是唯一涵蓋所有主要診斷影像模態（Diagnostic Imaging Modalities）的整合式小動物體內造影劑系列，包括：
- 磁振造影（MRI）：GadoSpin™ 和 FeraSpin™ 造影劑
- 電腦斷層掃描（CT）：ExiTron™ 造影劑
- 超音波影像（Ultrasound）：PolySon™ 造影劑
- 光學影像（Optical Imaging）：NiraWave™ 造影劑
- PET 和 SPECT 造影劑：即將推出
我們的產品包括創新的分子和藥理學（Novel Molecules and Pharmacologies），以及將臨床實踐中值得信賴的標準應用於動物影像研究。
Viscover™ 產品系列為眾多研究領域提供完整解決方案，涵蓋：
- 腫瘤學、心血管、發炎和神經學研究（Oncology, Cardiovascular, Inflammation, Neurology）
- 藥物研發（Drug Research and Development）
- 囓齒類動物的人類疾病模型（Human Disease Models in Rodents）
- 造影劑與影像設備研究（Contrast Agent and Imaging Device Research）
- 基礎研究：從體外到體內（Basic Research: from In Vitro to In Vivo）
Imaging Excellence | 影像操作簡便如 ABC
臨床前影像研究（Pre-clinical Imaging）如同 ABC 一樣簡單。Viscover™ 造影劑的開發理念是提供卓越的性能和可靠的結果，並具備最大的便利性。
Viscover™ 造影劑讓動物研究工作流程更加簡化：
A. 抽取 100 μL 造影劑（針對小鼠）
B. 注射到尾靜脈（Tail Vein）
C. 開始掃描（Scan）
就是這麼簡單！
- 即用型配方（Ready-to-use）：附有詳細的步驟說明
- 等滲無菌配方（Iso-osmolar Sterile Formulation）：確保安全性
- 單次劑量團注給藥（Single Dose Bolus Administration）：操作簡便
- 優異的耐受性（Excellent Tolerability）：僅需 100 μL 注射體積
- 統一的外觀和使用體驗：整個產品系列具有一致性
Viscover™ 開發團隊致力於動物福祉（Animal Welfare）和動物研究的「3R 原則」：替代（Replace）、減量（Reduce）、精緻化（Refine）。我們的造影劑經過優化，通過提供更精緻的影像品質，減少每項研究所需的動物數量，同時降低時間和成本支出。
Efficacy | 從物理學到效能：尖端奈米技術成就卓越影像
Viscover™ 的造影劑經過藥理學工程設計（Pharmacologically Engineered），為所有主要影像模態提供最佳的對比效率（Optimal Contrast Efficiencies）。
- FeraSpin 產品的超順磁性（Superparamagnetism）：提供卓越的 MRI 對比度
- ExiTron nano 產品的低粘度（Low Viscosity）：實現優異的 CT 影像
- PolySon 造影劑的增強回聲性（Enhanced Echogenicity）：提供出色的超音波對比
- NiraWave nano 產品的量子侷限效應（Quantum Confinement）：提供卓越的光學特性
Viscover™ 開發了穩健的粒子尺寸分離方法（Particle Size Fractionation）。FeraSpin 系列完美展示了這項技術，提供一系列尺寸分級的超順磁氧化鐵奈米粒子（Superparamagnetic Iron Oxide Nanoparticles）用於 MRI 研究。
粒子尺寸與特性的關係：
- 較小粒子（如 FeraSpin XS）：具有最長的循環時間（Circulation Times）
- 較大粒子（如 FeraSpin XXL）：更快速地在肝臟和脾臟中累積
- 較小粒子的優勢：具有適合 T1 加權「正對比」（T1-weighted Positive Contrast）的最佳特性，即低 r2/r1 弛緩比（Relaxivity Ratio）
- 較大粒子的優勢：具有更高的 T2 弛緩率（T2 Relaxation Rate），因此擁有最佳的 T2/T2* 對比特性
綜合而言，FeraSpin 系列涵蓋了用於 MRI 研究的完整氧化鐵奈米粒子尺寸範圍。
| FeraSpin™ 系列 | 平均粒子尺寸 （流體動力學直徑） | 弛緩比 r2/r1 （水溶液 37°C，1.41 T） |
|---|---|---|
| XS | 10 – 20 nm | 3 - 5 |
| S | 20 – 30 nm | 5 - 9 |
| M | 30 – 40 nm | 9 - 22 |
| L | 40 – 50 nm | 22 - 32 |
| XL | 50 – 60 nm | 32 - 39 |
| XXL | 60 – 70 nm | 39 - 46 |
Pharmacology | 從結構到藥理學：GadoSpin 產品家族展現 Viscover 的多功能性
Viscover™ 採用廣泛的結構實體（Structural Entities）來為您的特定應用量身打造造影劑。GadoSpin 產品家族完美展示了所有 Viscover 產品基礎的結構-功能協同作用（Structural-Functional Synergy），體現了產品的多功能性。
小分子造影劑（Small Molecular Agents）
- 快速從血管系統逃逸（Rapidly Escape from Vasculature）
- 不穿過細胞膜或完整的血腦屏障（Blood-Brain Barrier）
- 通常經歷快速的腎臟排泄（Rapid Renal Excretion）
血管外洩造影劑（Extravasating Agents）
- 被健康血管保留（Retained by Healthy Blood Vessels）
- 穿過血管變化的部位（Pass Through Sites of Vascular Changes）
- 非常適合血管通透性的動態研究（Dynamic Studies of Vascular Permeability）
血池造影劑（Blood Pool Agents）
- 在血管系統中長時間循環（Circulate for a Prolonged Period）
- 理想適用於血管造影掃描（Angiography Scans）
- 與白蛋白結合並避免快速腎臟排泄（Bind to Albumin）
- 在目標組織中富集，如動脈粥樣硬化斑塊和淋巴結（Atherosclerotic Plaques and Lymph Nodes）
顆粒造影劑（Particulate Agents）
- 避免腎臟排泄（Escape Renal Excretion）
- 長時間循環（Circulate for an Extended Time）
- 進入循環和駐留的吞噬細胞（Enter Circulating and Resident Phagocytes）
GadoSpin 產品涵蓋廣泛的結構實體。其明確定義的藥理學特性（Defined Pharmacologies）為研究人員提供了一套獨特的工具，適用於眾多影像應用。
影像作品集 | Data Gallery
瀏覽 Viscover™ 造影劑在實際研究中的應用成果，從 MRI 到 CT、從超音波到光學影像，每一張影像都展現了我們產品的專業實力和卓越品質。這些真實的研究案例證明了 Viscover™ 在小動物影像領域的領導地位。
瀏覽完整影像作品集 →
探索更多精彩的研究影像，了解 Viscover™ 造影劑如何為您的研究帶來突破性的影像品質。
客製化諮詢與服務 | Consulting and Service
我們致力於滿足客戶對客製化奈米藥物（Tailor-made Nanopharmaceuticals）和造影劑的需求。我們的客製化解決方案包括造影劑開發（Agent Development）、藥物製造（Pharmaceutical Manufacturing）以及實驗設計（Experiment Design）。
Viscover™ 是唯一能為所有影像模態提供標靶特異性造影劑（Target-specific Imaging Agents）的公司。
資源下載 | Resources
常見問題 | FAQ
About Viscover™ Imaging Agents
Viscover™ represents a landmark advancement in small animal in vivo imaging, offering the industry's first comprehensive portfolio of specialized pre-clinical imaging agents across all principal imaging modalities. As animal imaging rapidly gains relevance in pharmaceutical research and drug development, Viscover provides researchers with cutting-edge contrast agents that transform their imaging capabilities.
Our extensive product portfolio encompasses GadoSpin™ and FeraSpin™ contrast agents for MRI (magnetic resonance imaging), ExiTron™ contrast agents for CT (computed tomography), PolySon™ contrast agents for ultrasound imaging, NiraWave™ contrast agents for optical imaging, and FluoroWave dyes for application-specific fluorescence imaging. Using innovative nanotechnologies, most of our agents are far ahead of human clinical routine standards, yet we also provide clinical standard agents to meet diverse research needs.
Quality assurance is at the core of Viscover's commitment. Every contrast agent undergoes rigorous quality control processes and comprehensive testing to ensure consistency, stability, and reliability. Our advanced manufacturing techniques and standardized production workflows guarantee reproducible results that researchers can trust. From raw material selection to final product delivery, each step is meticulously monitored, providing complete documentation including Certificates of Analysis (CoA).
Imaging excellence defines the Viscover experience. Our contrast agents are designed to deliver superior image quality across all modalities. Through innovative nanotechnology and precise chemical engineering, Viscover agents provide exceptional organ specificity, tissue contrast, and high-resolution imaging. Whether you're conducting MRI, CT, ultrasound, or optical imaging research, our products enable clear visualization of tissue structures and pathological changes with outstanding contrast enhancement.
The efficacy of Viscover contrast agents stems from careful optimization of pharmacokinetic properties and biodistribution profiles. Our agents offer prolonged blood circulation times, efficient tissue penetration, and predictable in vivo behavior that facilitates experimental design. For example, the FeraSpin™ series features unique nanoparticle designs that provide extended circulation and specific organ accumulation, allowing researchers to capture optimal images within ideal time windows.
Understanding pharmacological properties is crucial for successful imaging research. Viscover provides comprehensive pharmacological data including absorption, distribution, metabolism, and excretion (ADME) information. Our contrast agents are designed with excellent biocompatibility and favorable safety profiles, minimizing impact on experimental animals while delivering superior imaging performance. This makes them ideal for longitudinal studies and repeated dosing protocols.
Viscover is the only company offering target-specific imaging agents for all imaging modalities. We provide tailored consulting and services to meet customer demands for custom nanopharmaceuticals and imaging agents. Our solutions encompass agent development, pharmaceutical manufacturing, and experiment design support. Collaboration opportunities range from pilot studies to long-term strategic partnerships, ensuring that researchers receive the precise tools and expertise needed for their specific projects.
Our MRI Portfolio includes advanced gadolinium-based (GadoSpin™) and iron oxide-based (FeraSpin™) contrast agents that transform pre-clinical MRI facilities. These agents provide exceptional T1 and T2 contrast enhancement, enabling detailed visualization of anatomical structures, disease progression, and therapeutic responses. The nanoparticle formulations offer superior performance compared to conventional clinical MRI contrast agents.
The CT Portfolio featuring ExiTron™ agents delivers superior contrast for exceptional imaging results. These blood pool and liver-specific contrast agents provide prolonged imaging windows and excellent contrast enhancement, making them ideal for cardiovascular studies, tumor imaging, and hepatic research. The long circulation times enable multiple scan time points from a single injection.
Our Ultrasound Portfolio with PolySon™ agents offers enhanced contrast for precise diagnostic imaging. These microbubble-based contrast agents improve visualization of blood flow, tissue perfusion, and vascular structures, supporting advanced ultrasound research applications including contrast-enhanced ultrasound (CEUS) and molecular imaging.
The Optical Imaging Portfolio comprises NiraWave™ near-infrared agents and FluoroWave fluorescent dyes for cutting-edge optical research. These agents enable high-sensitivity fluorescence imaging, bioluminescence studies, and multi-modal imaging approaches. The near-infrared wavelengths provide deep tissue penetration and low background interference, ideal for whole-body imaging applications.
Our Chemistry Portfolio provides customized chemical solutions tailored to specific research needs. From contrast agent development to pharmaceutical manufacturing, we offer comprehensive chemical technology support. This includes custom synthesis, chemical modifications, and formulation development to create specialized imaging agents that address unique research challenges.
The Viscover Data Gallery showcases real-world research applications and imaging outcomes achieved with our contrast agents. These authentic case studies demonstrate the professional capabilities and exceptional quality that position Viscover as a leader in small animal imaging. Researchers can explore diverse applications spanning oncology, cardiovascular research, neuroscience, and pharmaceutical development.
Viscover contrast agents are extensively used in preclinical imaging research, including drug discovery, pharmaceutical development, disease model studies, and translational research. The combination of high image quality, reliable performance, and comprehensive technical support makes Viscover the preferred choice for research institutions and pharmaceutical companies worldwide seeking to advance their imaging capabilities and accelerate scientific discovery.
For researchers requiring multimodal imaging approaches, Viscover offers the unique advantage of providing compatible agents across all major imaging platforms. This enables comprehensive characterization of biological processes through complementary imaging techniques, enhancing research insights and experimental outcomes.